Communication

Nano- and Micropatterning of Optically Transparent, Mechanically Robust, Biocompatible Silk Fibroin Films†

  1. Hannah Perry1,
  2. Ashwin Gopinath2,
  3. David L. Kaplan1,
  4. Luca Dal Negro2,*,
  5. Fiorenzo G. Omenetto1,*

Article first published online: 7 JUL 2008

DOI: 10.1002/adma.200800011

Issue

Advanced Materials

Advanced Materials

Volume 20, Issue 16, pages 3070–3072, August 18, 2008

Additional Information

How to Cite

Perry, H., Gopinath, A., Kaplan, D. L., Dal Negro, L. and Omenetto, F. G. (2008), Nano- and Micropatterning of Optically Transparent, Mechanically Robust, Biocompatible Silk Fibroin Films. Adv. Mater., 20: 3070–3072. doi: 10.1002/adma.200800011

Author Information

  1. 1

    Department of Biomedical Engineering Tufts University 4 Colby St., Medford, MA (USA)

  2. 2

    Department of Electrical and Computer Engineering Boston University 8 Saint Mary's St., Boston, MA (USA)

*Department of Electrical and Computer Engineering Boston University 8 Saint Mary's St., Boston, MA (USA).

  1. †

    This work was supported by the DARPA, AFOSR, Tufts School of Engineering, and by the College of Engineering Dean's Catalyst Award at Boston University. The authors would like to thank Jessica Wargats of Digital Optics Inc./Tessera. for the diffractive optics sample.

Publication History

  1. Issue published online: 14 AUG 2008
  2. Article first published online: 7 JUL 2008
  3. Manuscript Revised: 6 FEB 2008
  4. Manuscript Received: 2 JAN 2008

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Keywords:

  • biocompatible materials;
  • proteins;
  • surface patterning
Thumbnail image of graphical abstract

Regular nanometer-scale patterning down to a few tens of nanometers and the manufacturing of diffractive optical elements in silk by using the ideas of soft lithography is reported. The unique processing of silk films makes them an ideal substrate to incorporate biological matter (such as small organics, enzymes, proteins, cells). Unprecedented definition in the transverse direction, with features down to few tens of nanometers, is reported.

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