Communication

Core/Single-Crystal-Shell Nanospheres for Controlled Drug Release via a Magnetically Triggered Rupturing Mechanism†

  1. Shang-Hsiu Hu,
  2. San-Yuan Chen*,
  3. Dean-Mo Liu*,
  4. Chi-Sheng Hsiao

Article first published online: 2 JUN 2008

DOI: 10.1002/adma.200800193

Issue

Advanced Materials

Advanced Materials

Volume 20, Issue 14, pages 2690–2695, July 17, 2008

Additional Information

How to Cite

Hu, S.-H., Chen, S.-Y., Liu, D.-M. and Hsiao, C.-S. (2008), Core/Single-Crystal-Shell Nanospheres for Controlled Drug Release via a Magnetically Triggered Rupturing Mechanism. Advanced Materials, 20: 2690–2695. doi: 10.1002/adma.200800193

Author Information

  1. Department of Materials Sciences and Engineering National Chiao Tung University Hsinchu 300 (Taiwan)

*Department of Materials Sciences and Engineering National Chiao Tung University Hsinchu 300 (Taiwan).

  1. †

    This work was financially supported by the National Science Council of the Republic of China, Taiwan under Contract No. NSC96-2627- B-009-006 and No. NSC96-2113-M009-027-MY2. We also thank Dr. C. H. Bow for TEM analysis. Supporting Information is available online from Wiley InterScience or from the authors.

Publication History

  1. Issue published online: 23 JUL 2008
  2. Article first published online: 2 JUN 2008
  3. Manuscript Revised: 3 MAR 2008
  4. Manuscript Received: 21 JAN 2008

Funded by

  • National Science Council of the Republic of China, Taiwan. Grant Numbers: NSC96-2627- B-009-006, NSC96-2113-M009-027-MY2

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Keywords:

  • drug delivery;
  • controlled release;
  • nanocapsules;
  • core/shell materials;
  • stimuli-responsive materials

Graphical Abstract

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Core/single-crystal-shell nanospheres are constructed from a poly-(N-vinyl- 2-pyrrolidone) (PVP)-modified silica core with an outer layer of single-crystal iron oxide shell. The nanospheres show outstanding release-and-zero-release characteristics via the addition and removal, respectively, of an external high-frequency magnetic field.

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