This work was funded in part by Northwestern University's Materials Research Science and Engineering Center. Supporting Information is available online from Wiley InterScience or from the author.
Nanoporous Biodegradable Elastomers†
Article first published online: 4 NOV 2008
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 21, Issue 2, pages 188–192, January 12, 2009
How to Cite
Hoshi, R. A., Behl, S. and Ameer, G. A. (2009), Nanoporous Biodegradable Elastomers. Adv. Mater., 21: 188–192. doi: 10.1002/adma.200801132
- Issue published online: 2 JAN 2009
- Article first published online: 4 NOV 2008
- Manuscript Revised: 4 SEP 2008
- Manuscript Received: 24 APR 2008
- Northwestern University's Materials Research Science and Engineering Center
- biodegradable polymers;
- drug delivery;
- nanoporous materials
A nanoporous biodegradable elastomer based on citric acid is described. Nanopores are used to control the mechanical and degradation properties of the elastomer. Furthermore, macromolecular drugs can be entrapped under mild conditions via pore collapse, which also delays the release of the drug. The nanoporous elastomer is biocompatible and a promising platform technology for engineering soft tissues.