Communication

Nanoporous Biodegradable Elastomers†

  1. Ryan A. Hoshi1,
  2. Saloni Behl1,
  3. Guillermo A. Ameer1,2,3,*

Article first published online: 4 NOV 2008

DOI: 10.1002/adma.200801132

Issue

Advanced Materials

Advanced Materials

Volume 21, Issue 2, pages 188–192, January 12, 2009

Additional Information

How to Cite

Hoshi, R. A., Behl, S. and Ameer, G. A. (2009), Nanoporous Biodegradable Elastomers. Adv. Mater., 21: 188–192. doi: 10.1002/adma.200801132

Author Information

  1. 1

    Biomedical Engineering Department, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (USA)

  2. 2

    Department of Surgery Northwestern University Feinberg School of Medicine 201 E Huron St., Chicago, IL 60611 (USA)

  3. 3

    The Institute for BioNanotechnology in Medicine Northwestern University 303 E. Superior, Chicago, IL 60611 (USA)

*Biomedical Engineering Department, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (USA).

  1. †

    This work was funded in part by Northwestern University's Materials Research Science and Engineering Center. Supporting Information is available online from Wiley InterScience or from the author.

Publication History

  1. Issue published online: 2 JAN 2009
  2. Article first published online: 4 NOV 2008
  3. Manuscript Revised: 4 SEP 2008
  4. Manuscript Received: 24 APR 2008

Funded by

  • Northwestern University's Materials Research Science and Engineering Center

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Keywords:

  • biodegradable polymers;
  • biomaterials;
  • drug delivery;
  • elastomers;
  • nanoporous materials
Thumbnail image of graphical abstract

A nanoporous biodegradable elastomer based on citric acid is described. Nanopores are used to control the mechanical and degradation properties of the elastomer. Furthermore, macromolecular drugs can be entrapped under mild conditions via pore collapse, which also delays the release of the drug. The nanoporous elastomer is biocompatible and a promising platform technology for engineering soft tissues.

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