Communication

Electrospun Nanofibrous Membranes: A Novel Solid Substrate for Microfluidic Immunoassays for HIV†

  1. Dayong Yang1,2,
  2. Xin Niu1,
  3. Yingyi Liu1,
  4. Yang Wang1,
  5. Xuan Gu1,
  6. Lusheng Song1,2,
  7. Rui Zhao1,
  8. Liying Ma3,
  9. Yiming Shao3,
  10. Xingyu Jiang1,*

Article first published online: 22 OCT 2008

DOI: 10.1002/adma.200801302

Issue

Advanced Materials

Advanced Materials

Volume 20, Issue 24, pages 4770–4775, December 17, 2008

Additional Information

How to Cite

Yang, D., Niu, X., Liu, Y., Wang, Y., Gu, X., Song, L., Zhao, R., Ma, L., Shao, Y. and Jiang, X. (2008), Electrospun Nanofibrous Membranes: A Novel Solid Substrate for Microfluidic Immunoassays for HIV. Adv. Mater., 20: 4770–4775. doi: 10.1002/adma.200801302

Author Information

  1. 1

    National Center for NanoScience and Technology 11 Beiyitiao, ZhongGuanCun Beijing 100190 (China)

  2. 2

    Graduate School of the Chinese Academy of Sciences Beijing 100864 (China)

  3. 3

    Chinese Center for Disease Control and Prevention Beijing 100050 (China)

*National Center for NanoScience and Technology 11 Beiyitiao, ZhongGuanCun Beijing 100190 (China).

  1. †

    We thank Prof. Lei Jiang and Prof. Meng He for the help with the equipment for ES. This work was supported by the CAS Innovation Program, the National Science Foundation of China (20605006 and 20890020) and the Ministry of Science and Technology (2006CB705600, 2006AA03Z323 and 2009CB930001).

Publication History

  1. Issue published online: 16 DEC 2008
  2. Article first published online: 22 OCT 2008
  3. Manuscript Revised: 11 AUG 2008
  4. Manuscript Received: 11 MAY 2008

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Keywords:

  • electrospinning;
  • nanofibers;
  • membranes;
  • microfluidic systems;
  • bionanotechnology
Thumbnail image of graphical abstract

The combination of electrospun nanofibrous membranes and microfluidic channels dramatically improves the sensitivities of HIV immunoassays in microfluidic channels. Simplicity and effectiveness of the new system can potentially pave the way for inexpensive, portable and highly sensitive diagnostic devices.

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