The authors would like to thank the European Framework 6 plan for funding (COOP. CT-2005-018060). Supporting Information is available online from Wiley InterScience or from the author.
Bone-like Resorbable Silk-based Scaffolds for Load-bearing Osteoregenerative Applications†
Article first published online: 10 NOV 2008
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 21, Issue 1, pages 75–78, January 5, 2009
How to Cite
Collins, A. M., Skaer, N. J. V., Gheysens, T., Knight, D., Bertram, C., Roach, H. I., Oreffo, R. O. C., Von-Aulock, S., Baris, T., Skinner, J. and Mann, S. (2009), Bone-like Resorbable Silk-based Scaffolds for Load-bearing Osteoregenerative Applications. Adv. Mater., 21: 75–78. doi: 10.1002/adma.200802239
- Issue published online: 2 JAN 2009
- Article first published online: 10 NOV 2008
- Manuscript Revised: 22 SEP 2008
- Manuscript Received: 1 AUG 2008
- European Framework 6 plan. Grant Number: COOP. CT-2005-018060
- biomedical materials;
- tissue engineering
Hydroxyapatite/silk biocompatible composites with unprecedented mechanical strength and toughness areproduced in a new process with theintegrated mineralization of macroporous silk fibroin scaffolds. Thebiomimetic bone-like composites areabsorbable and load-bearing with compressive strength, modulus, andtoughness comparable to the mechanical tolerances of cancellous bone.