Generation of Bioactive Materials with Rapid Self-Assembling Resorcinarene-Peptides



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Adhesive resorcinarene molecules rapidly self-assemble on a wide range of material surfaces. We have created resorcinarenes that contain a biologically active terminal GKP-D-V anti-inflammatory peptide by a rapid “dip-and-dry” forming method. The growth of neural Schwann and fibroblast cells on a layer of resorcinarene-GKP-D-V demonstrate inhibition of inflammatory signaling.