Core-Sheath Nanofibers Containing Colloidal Arrays in the Core for Programmable Multi-Agent Delivery



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Polymeric core-sheath nanofibers consisting of polymeric sheath and arrays of colloids in the core are produced by one-step single-nozzle electrospinning. Loading different species of active agents in each colloid provides control over the release of each of the agents independently, which enables a programmed release pattern for multiple agents.