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Keywords:

  • Cell adhesion;
  • Fibronectin activity;
  • High throughput;
  • Human embryonic stem cells;
  • Polymer array
Thumbnail image of graphical abstract

An integrated high-throughput polymer synthesis and rapid material/protein/cell interaction assays were developed to optimize stem cell microenvironments. Microarrayed polymers were synthesized and studied for the ability to support the growth of partially differentiated human embryonic stem cells. In parallel, a programmed laser scanning cytometry system was developed to allow for rapid quantification of cell material interaction.