Advertisement

Magnetically Triggered Reversible Controlled Drug Delivery from Microfabricated Polymeric Multireservoir Devices

Authors

  • Kaiyong Cai,

    Corresponding author
    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    • Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China).
    Search for more papers by this author
  • Zhong Luo,

    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    Search for more papers by this author
  • Yan Hu,

    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    Search for more papers by this author
  • Xiuyong Chen,

    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    Search for more papers by this author
  • Yanjian Liao,

    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    Search for more papers by this author
  • Li Yang,

    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    Search for more papers by this author
  • Linhong Deng

    1. Key Laboratory of Biorheological Science and Technology Ministry of Education College of Bioengineering Chongqing University Chongqing, 400044 (P.R. China)
    Search for more papers by this author

Abstract

original image

The pulsed reversible release of dual drugs from biodegradable polymeric multireservoir devices is successfully demonstrated. The controlled release is achieved by incorporating magnetic particles in the devices as switch carriers. It is possible to intentionally switch on/off the drug release at any desired time for a chosen duration.

Ancillary