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Keywords:

  • biosensor;
  • liposome microarray;
  • mercury detection;
  • polydiacetylene;
  • self-assembly
Thumbnail image of graphical abstract

Polydiacetylene (PDA) liposome microarrays are developed for selective and sensitive mercury (Hg2+) detection. The PDA mercury sensors are designed to produce red fluorescence emission upon binding with Hg2+, when the ssDNA aptamers on the PDA surface recognize and wrap around mercury ions and the resulting bulky T-Hg-T complexes repulse each other.