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Polydiacetylene–Liposome Microarrays for Selective and Sensitive Mercury(II) Detection

Authors

  • Jiseok Lee,

    1. Macromolecular Science and Engineering University of Michigan Ann Arbor, MI 48109 (USA)
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  • Hayeon Jun,

    1. Department of Material Science and Engineering University of Michigan Ann Arbor, MI 48109 (USA)
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  • Jinsang Kim

    Corresponding author
    1. Macromolecular Science and Engineering University of Michigan Ann Arbor, MI 48109 (USA)
    2. Department of Material Science and Engineering University of Michigan Ann Arbor, MI 48109 (USA)
    3. Chemical Engineering University of Michigan Ann Arbor, MI 48109 (USA)
    4. Biomedical Engineering University of Michigan Ann Arbor, MI 48109 (USA)
    • Macromolecular Science and Engineering University of Michigan Ann Arbor, MI 48109 (USA).
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Abstract

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Polydiacetylene (PDA) liposome microarrays are developed for selective and sensitive mercury (Hg2+) detection. The PDA mercury sensors are designed to produce red fluorescence emission upon binding with Hg2+, when the ssDNA aptamers on the PDA surface recognize and wrap around mercury ions and the resulting bulky T-Hg-T complexes repulse each other.

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