Communication

Free-Standing Biodegradable Poly(lactic acid) Nanosheet for Sealing Operations in Surgery

  1. Yosuke Okamura1,
  2. Koki Kabata1,
  3. Manabu Kinoshita2,
  4. Daizoh Saitoh3,
  5. Shinji Takeoka1,*

Article first published online: 1 JUL 2009

DOI: 10.1002/adma.200901035

Issue

Advanced Materials

Advanced Materials

Volume 21, Issue 43, pages 4388–4392, November 20, 2009

Additional Information

How to Cite

Okamura, Y., Kabata, K., Kinoshita, M., Saitoh, D. and Takeoka, S. (2009), Free-Standing Biodegradable Poly(lactic acid) Nanosheet for Sealing Operations in Surgery. Adv. Mater., 21: 4388–4392. doi: 10.1002/adma.200901035

Author Information

  1. 1

    Department of Life Science and Medical Bioscience Graduate School of Advanced Science and Engineering Waseda University, TWIns Shinjuku-ku, Tokyo, 162-8480 (Japan)

  2. 2

    Department of Immunology and Microbiology National Defense Medical College Tokorozawa, Saitama, 359-8513 (Japan)

  3. 3

    Division of Traumatology National Defense Medical College Tokorozawa, Saitama, 359-8513 (Japan)

*Department of Life Science and Medical Bioscience Graduate School of Advanced Science and Engineering Waseda University, TWIns Shinjuku-ku, Tokyo, 162-8480 (Japan).

Publication History

  1. Issue published online: 19 NOV 2009
  2. Article first published online: 1 JUL 2009
  3. Manuscript Revised: 10 MAY 2009
  4. Manuscript Received: 26 MAR 2009

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Keywords:

  • biocompatible materials;
  • lactic acid;
  • nanosheets;
  • surgery
Thumbnail image of graphical abstract

A free-standing biodegradable nanosheet composed of poly(L-lactic acid) (PLLA) was shown to have excellent sealing efficacy for a gastric incision as a novel wound dressing material that did not require adhesive agents, and the PLLA nanosheet-induced wound repair showed neither scars nor tissue adhesion. This material may, therefore, be an ideal alternative to conventional tissue repairing procedures using suture/ligation in surgery.

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