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Keywords:

  • angiogenesis;
  • capillary morphogenesis;
  • microfluidics
Thumbnail image of graphical abstract

Robust induction of realistic angiogenesis into a 3D matrix material under simultaneous imaging and a stably controlled concentration gradient of chemoattractants is presented. The formation of a 3D vascular network is demonstrated to be a direct consequence of surface treatment of the region of the device-containing matrix material.