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Microcrimped Collagen Fiber-Elastin Composites

Authors

  • Jeffrey M. Caves,

    1. Departments of Biomedical Engineering and Surgery Emory University/Georgia Institute of Technology 101 Woodruff Circle, Rm 5105, Atlanta, GA 30322 (USA)
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  • Vivek A. Kumar,

    1. Departments of Biomedical Engineering and Surgery Emory University/Georgia Institute of Technology 101 Woodruff Circle, Rm 5105, Atlanta, GA 30322 (USA)
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  • Wenjun Xu,

    1. Schools of Electrical and Computer Engineering, Georgia Institute of Technology 791 Atlantic Dr., MiRC 120, Atlanta, GA 30332 (USA)
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  • Nisarga Naik,

    1. Schools of Electrical and Computer Engineering, Georgia Institute of Technology 791 Atlantic Dr., MiRC 120, Atlanta, GA 30332 (USA)
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  • Mark G. Allen,

    1. Schools of Electrical and Computer Engineering, Georgia Institute of Technology 791 Atlantic Dr., MiRC 120, Atlanta, GA 30332 (USA)
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  • Elliot L. Chaikof

    Corresponding author
    1. Departments of Biomedical Engineering and Surgery Emory University/Georgia Institute of Technology 101 Woodruff Circle, Rm 5105, Atlanta, GA 30322 (USA)
    • Departments of Biomedical Engineering and Surgery Emory University/Georgia Institute of Technology 101 Woodruff Circle, Rm 5105, Atlanta, GA 30322 (USA).
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Abstract

A flexible membrane templating technique (a) is developed for the fabrication of microcrimped collagen microfibers (b) that are embedded in an elastin-like protein matrix to generate hierarchical, biologically inspired fiber-reinforced composites (c). The microcrimped structure is stable under cyclic loading and the mechanical response of the engineered collagen-elastin composite mimics that of native tissue.

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