Graphene Oxide: Intrinsic Peroxidase Catalytic Activity and Its Application to Glucose Detection

Authors

  • Yujun Song,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences Changchun, Jilin 130022 (China)
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  • Konggang Qu,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences Changchun, Jilin 130022 (China)
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  • Chao Zhao,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences Changchun, Jilin 130022 (China)
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  • Jinsong Ren,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences Changchun, Jilin 130022 (China)
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  • Xiaogang Qu

    Corresponding author
    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences Changchun, Jilin 130022 (China)
    • Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences Changchun, Jilin 130022 (China).
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Abstract

original image

Carboxyl-modified graphene oxide (GO–COOH) possesses intrinsic peroxidase-like activity that can catalyze the reaction of peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue color reaction. A simple, cheap, and highly sensitive and selective colorimetric method for glucose detection has been developed and will facilitate the utilization of GO[BOND]COOH intrinsic peroxidase activity in medical diagnostics and biotechnology.

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