Advanced Materials

Magnetic-Field-Assisted Electrospinning of Aligned Straight and Wavy Polymeric Nanofibers

Authors

  • Yaqing Liu,

    1. Department of Chemical Engineering, University of Rochester Gavett Hall 206, Rochester, NY 14627-0166 (USA)
    2. Shanxi Research Center for Engineering Technology of Polymeric Composites North University of China Taiyuan, 030051 (P. R. China)
    Search for more papers by this author
  • Xinping Zhang,

    1. Center for Musculoskeletal Research, School of Medicine and Dentistry University of Rochester Rochester, NY 14642 (USA)
    Search for more papers by this author
  • Younan Xia,

    1. Department of Biomedical Engineering Washington University in St. Louis St. Louis, MO 63130-4899 (USA)
    Search for more papers by this author
  • Hong Yang

    Corresponding author
    1. Department of Chemical Engineering, University of Rochester Gavett Hall 206, Rochester, NY 14627-0166 (USA)
    • Department of Chemical Engineering, University of Rochester Gavett Hall 206, Rochester, NY 14627-0166 (USA).
    Search for more papers by this author

Abstract

Aligned straight and wavy fibers of biodegradable poly(D,L-lactic-co-glycolic acid) (PLGA) are fabricated using a magnetic-field-assisted electrospinning method. PLGA fibrous matrices prepared by this method can guide the growth of pluripotent murine mesenchymal stem cells. While the stem cells on the randomly oriented fibers adapt pseudo-sphere-like shape, those on aligned fibers exhibit elongated morphology along the long axes (see figure).

original image

Ancillary