Advanced Materials

Micro-Masonry: Construction of 3D Structures by Microscale Self-Assembly

Authors

  • Javier G. Fernandez,

    1. Center for Biomedical Engineering, Department of Medicine Brigham and Women's Hospital Harvard Medical School Boston, MA (USA)
    2. Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology Cambridge, MA (USA)
    3. The Wyss Institute for Biologically Inspired Engineering Harvard University Boston, MA (USA)
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  • Ali Khademhosseini

    Corresponding author
    1. Center for Biomedical Engineering, Department of Medicine Brigham and Women's Hospital Harvard Medical School Boston, MA (USA)
    2. Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology Cambridge, MA (USA)
    3. The Wyss Institute for Biologically Inspired Engineering Harvard University Boston, MA (USA)
    • Center for Biomedical Engineering, Department of Medicine Brigham and Women's Hospital Harvard Medical School Boston, MA (USA).
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Abstract

A biocompatible method for general construction of 3D structures by aggregation of micrometric polymeric subunits is presented. Shape-controlled microgels are forced to self-assemble, in a structure similar to a brick wall, in different shapes by limiting their movement onto a surface. Scaffolds with high spatial resolution in the aggregation and composed by the addition of multiple layers are produced.

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