Biomedical Materials: Nanoporous Biodegradable Elastomers (Adv. Mater. 2/2009)

Authors

  • Ryan A. Hoshi,

    1. Biomedical Engineering Department, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (USA)
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  • Saloni Behl,

    1. Biomedical Engineering Department, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (USA)
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  • Guillermo A. Ameer

    Corresponding author
    1. Biomedical Engineering Department, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (USA)
    2. Department of Surgery Northwestern University Feinberg School of Medicine 201 E Huron St., Chicago, IL 60611 (USA)
    3. The Institute for BioNanotechnology in Medicine Northwestern University 303 E. Superior, Chicago, IL 60611 (USA)
    • Biomedical Engineering Department, Northwestern University 2145 Sheridan Road, Evanston, IL 60208 (USA).
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Abstract

original image

The mechanical properties and degradation rate of elastomers can be tailored with nanoporosity. The elastomers described in this study by Guillermo Ameer and co-workers (p. 188) are based on citric acid and are biocompatible. The nanopores also facilitate the entrapment and slow release of macromolecular therapeutics. The inside cover depicts the nano- and microarchitecture of the elastomer prior to pore collapse.

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