DNA Hybrid Nanomachines: Fullerene Attachment Enhances Performance of a DNA Nanomachine (Adv. Mater. 19/2009)



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The image shows the developing biocompatible molecules with controllable, accurate, and reproducible molecular motor functions for mobile nanodevices. Seon Jeong Kim and co-workers show on page 1907 that the attachment of fullerene moieties to a single-strand DNA significantly improves the molecular switching and stability of this pH driven enthalpic molecular machine. Hydrophobic interactions between the terminal fullerenes in the folded i-motif conformation increased the machines power stroke and force generated.