Artificial DNA Nano-Spring Powered by Protons

Authors

  • Chunyan Wang,

    1. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China)
    2. Graduate School of the Chinese Academy of Sciences, Beijing 100039 (P.R. China)
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  • Zhenzhen Huang,

    1. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China)
    2. Graduate School of the Chinese Academy of Sciences, Beijing 100039 (P.R. China)
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  • Youhui Lin,

    1. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China)
    2. Graduate School of the Chinese Academy of Sciences, Beijing 100039 (P.R. China)
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  • Jinsong Ren,

    Corresponding author
    1. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China)
    2. Graduate School of the Chinese Academy of Sciences, Beijing 100039 (P.R. China)
    • Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China).
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  • Xiaogang Qu

    1. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China)
    2. Graduate School of the Chinese Academy of Sciences, Beijing 100039 (P.R. China)
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Abstract

original image

A novel multifunctional, proton-fueled DNA nano-spring has been constructed. By incorporation of the G-quadruplex/i-motif sequence into the assembly, the nanodevice can perform spring-like motions in response to changes in the environmental pH without permanent deformation. Nanosized objects/functional groups could be assembled/disassembled into this system in an addressable, contractile, and reversible manner.

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