Non-invasive Detection of Cellular Bioelectricity Based on Carbon Nanotube Devices for High-Throughput Drug Screening

Authors

  • Tze-Sian Pui,

    1. Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, 637457 (Singapore)
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  • Herry Gunadi Sudibya,

    1. Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, 637457 (Singapore)
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  • Xuena Luan,

    1. Division of Microelectronic, School of Electrical & Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 (Singapore)
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  • Qing Zhang,

    1. Division of Microelectronic, School of Electrical & Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 (Singapore)
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  • Feng Ye,

    1. Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, 637457 (Singapore)
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  • Yinxi Huang,

    1. Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, 637457 (Singapore)
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  • Peng Chen

    Corresponding author
    1. Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, 637457 (Singapore)
    • Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, 637457 (Singapore).
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Abstract

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Nanoelectronic biosensors based on readily fabricated networks of single-walled carbon nanotubes (SWNT-net) were used to non-invasively detect cellular bioelectrical signals. This nanotube approach promises applications in both fundamental research and high-throughput drug screening targeting on ion channels.

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