Communication

Synergistic Cancer Therapeutic Effects of Locally Delivered Drug and Heat Using Multifunctional Nanoparticles

  1. Sun-Mi Lee1,
  2. Huiyul Park1,
  3. Kyung-Hwa Yoo1,2,*

Article first published online: 21 JUL 2010

DOI: 10.1002/adma.201001040

Issue

Advanced Materials

Advanced Materials

Volume 22, Issue 36, pages 4049–4053, September 22, 2010

Additional Information

How to Cite

Lee, S.-M., Park, H. and Yoo, K.-H. (2010), Synergistic Cancer Therapeutic Effects of Locally Delivered Drug and Heat Using Multifunctional Nanoparticles. Adv. Mater., 22: 4049–4053. doi: 10.1002/adma.201001040

Author Information

  1. 1

    National Core Research Center for Nanomedical Technology, Yonsei University, Seoul, 120–749 (Korea)

  2. 2

    Department of Physics, Yonsei University, Seoul, 120–749 (Korea)

*National Core Research Center for Nanomedical Technology, Yonsei University, Seoul, 120–749 (Korea).

Publication History

  1. Issue published online: 16 SEP 2010
  2. Article first published online: 21 JUL 2010
  3. Manuscript Revised: 12 APR 2010
  4. Manuscript Received: 23 MAR 2010

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Keywords:

  • chemo-photothermal therapy;
  • NIR resorance;
  • multifunctional nanoparticle;
  • local delivery of drug/heat;
  • in vivo imaging
Thumbnail image of graphical abstract

Doxorubicin-loaded PEG-PLGA-Au half-shell nanoparticles provide multifunctions, such as photothermal treatment, photothermally controlled drug delilvery, and in vivo optical imaging. In addition, the combined doxorubicin and photothermal treatments using these multifunctional nanoparticles show synergistic therapeutic effects.

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