Advanced Materials

Synergistic Cancer Therapeutic Effects of Locally Delivered Drug and Heat Using Multifunctional Nanoparticles

Authors

  • Sun-Mi Lee,

    1. National Core Research Center for Nanomedical Technology, Yonsei University, Seoul, 120–749 (Korea)
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  • Huiyul Park,

    1. National Core Research Center for Nanomedical Technology, Yonsei University, Seoul, 120–749 (Korea)
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  • Kyung-Hwa Yoo

    Corresponding author
    1. National Core Research Center for Nanomedical Technology, Yonsei University, Seoul, 120–749 (Korea)
    2. Department of Physics, Yonsei University, Seoul, 120–749 (Korea)
    • National Core Research Center for Nanomedical Technology, Yonsei University, Seoul, 120–749 (Korea).
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Abstract

Doxorubicin-loaded PEG-PLGA-Au half-shell nanoparticles provide multifunctions, such as photothermal treatment, photothermally controlled drug delilvery, and in vivo optical imaging. In addition, the combined doxorubicin and photothermal treatments using these multifunctional nanoparticles show synergistic therapeutic effects.

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