SEARCH

SEARCH BY CITATION

Keywords:

  • Thin Films;
  • Nanoparticles;
  • Polymeric Materials;
  • Drug Delivery
Thumbnail image of graphical abstract

Multilayer-coated microneedles achieve transcutaneous delivery of plasmid DNA to the viable epidermis. Cy3-labeled plasmid DNA encoding luciferase (yellow) is deposited on biodegradable microneedle arrays through multilayer self-assembly and then delivered to the skin by microneedle application to achieve colocalization with Langerhans dendritic cells (MHC II-GFP–green).