Advanced Materials

Two-Component Polymer Scaffolds for Controlled Three-Dimensional Cell Culture

Authors

  • Franziska Klein,

    1. KIT (Karlsruhe Institute of Technology), Zoologisches Institut, Zell- und Neurobiologie, Haid-und-Neu-Straße 9, D-76131 Karlsruhe, Germany
    2. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    Current affiliation:
    1. F.K. and B.R. contributed equally to this work.
    Search for more papers by this author
  • Benjamin Richter,

    1. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    2. KIT (Karlsruhe Institute of Technology), Institut für Angewandte Physik, Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    Current affiliation:
    1. F.K. and B.R. contributed equally to this work.
    Search for more papers by this author
  • Thomas Striebel,

    1. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    2. KIT (Karlsruhe Institute of Technology), Institut für Angewandte Physik, Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    Search for more papers by this author
  • Clemens M. Franz,

    1. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    Search for more papers by this author
  • Georg von Freymann,

    1. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    2. KIT (Karlsruhe Institute of Technology), Institut für Angewandte Physik, Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    Search for more papers by this author
  • Martin Wegener,

    1. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    2. KIT (Karlsruhe Institute of Technology), Institut für Angewandte Physik, Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    3. KIT (Karlsruhe Institute of Technology), Institut für Nanotechnologie, Hermann-von-Helmholtz-Platz 1, D-76021 Karlsruhe, Germany
    Search for more papers by this author
  • Martin Bastmeyer

    Corresponding author
    1. KIT (Karlsruhe Institute of Technology), Zoologisches Institut, Zell- und Neurobiologie, Haid-und-Neu-Straße 9, D-76131 Karlsruhe, Germany
    2. KIT (Karlsruhe Institute of Technology), DFG-Center for Functional Nanostructures (CFN), Wolfgang-Gaede-Straße 1, D-76131 Karlsruhe, Germany
    • KIT (Karlsruhe Institute of Technology), Zoologisches Institut, Zell- und Neurobiologie, Haid-und-Neu-Straße 9, D-76131 Karlsruhe, Germany.
    Search for more papers by this author

Abstract

Two-component 3D polymer scaffolds with distinct mechanical and protein-binding properties are fabricated using direct laser writing. With this method, full control over the formation of cell adhesion sites and, consequently, cell shape in three dimensions can be achieved.

original image

Ancillary