Synthesis of Monodisperse Microparticles from Non-Newtonian Polymer Solutions with Microfluidic Devices

Authors

  • Adam R. Abate,

    1. Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA
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  • Mikhail Kutsovsky,

    1. Buckingham Browne and Nichols School, 80 Gerry’s Landing Road, Cambridge, Massachusetts 02138, USA
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  • Sebastian Seiffert,

    1. Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA
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  • Maike Windbergs,

    1. Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA
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  • Luis F. V. Pinto,

    1. Universidade Nova de Lisboa, Departamento de Ciência dos Materiais and CENIMAT/I3N, Faculdade de Ciências e Tecnologia, Campus da FCT, Quinta da Torre, 2825–114 Caparica, Portugal
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  • Assaf Rotem,

    1. Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA
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  • Andrew S. Utada,

    1. Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA
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  • David A. Weitz

    Corresponding author
    1. Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA
    • Harvard University, School of Engineering and Applied Sciences and Department of Physics, 29 Oxford Street, Cambridge, Massachusetts 02138, USA.
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Abstract

original image

Polymer solutions are useful precursors to synthesize microparticles with microfluidic devices, but most polymer solutions are incompatible with microfluidic emulsification due to their non-Newtonian flow characteristics. A technique is presented to form monodisperse particles from such solutions by surrounding them with a chaperoning Newtonian fluid and forcing both to pinch into preparticle drops.

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