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Novel Biodegradable Shape-Memory Elastomers with Drug-Releasing Capabilities

Authors

  • M. Concepcion Serrano,

    1. Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA
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  • Luis Carbajal,

    1. Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA
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  • Guillermo A. Ameer

    Corresponding author
    1. Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA
    2. Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA
    3. Institute for BioNanotechnology in Medicine, Northwestern University, Chicago, IL 60611, USA
    4. Division of Vascular Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    • Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA.
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Abstract

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Novel polydiolcitrate elastomers with thermally induced shape-memory properties are synthesized. These thermoresponsive polymers can be prepared as films or porous 3D sponges. Above their transition temperature, these materials display an elastomeric behavior, but below their transition temperature they have a glassy state. This thermally induced transition allows for the acquisition of their dual shape.

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