Advanced Materials

Omnidirectional Printing of 3D Microvascular Networks

Authors

  • Willie Wu,

    1. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
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  • Adam DeConinck,

    1. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
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  • Jennifer A. Lewis

    Corresponding author
    1. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
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Abstract

3D biomimetic microvascular networks of nearly arbitrary design are patterned by omnidirectional printing of a fugitive organic ink into a photopolymerizable hydrogel matrix. This novel approach hinges critically on tailoring the chemical and rheological properties of the fugitive ink as well as the photopolymerizable hydrogel reservoir and fluid filler. These hydrogel-based, microvascular constructs may find potential application in 3D cell culture, tissue engineering, organ modeling, and autonomic healing.

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