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Presentation of BMP-2 from a Soft Biopolymeric Film Unveils its Activity on Cell Adhesion and Migration



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The dramatic effect of morphogenetic protein 2 (BMP-2), presented to cells in a “matrix bound” manner is described. BMP-2 is either delivered in solution or bound to a thin film made of poly(lysine) and hyaluronan. In this later case only, a striking effect of BMP-2 on cell adhesion and migration is observed.