Tissue Engineering: A Modular, Hydroxyapatite-Binding Version of Vascular Endothelial Growth Factor (Adv. Mater. 48/2010)

Authors

  • Jae Sung Lee,

    1. Department of Biomedical Engineering, University of Wisconsin, 1550 Engineering Drive, Madison, WI 53706 (USA)
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  • Amy J. Wagoner Johnson,

    1. Department of Mechanical Science and Engineering, University of Illinois, 1206 West Green Street, Urbana, IL 61801 (USA)
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  • William L. Murphy

    Corresponding author
    1. Department of Biomedical Engineering, University of Wisconsin, 1550 Engineering Drive, Madison, WI 53706 (USA)
    2. Department of Orthopedics and Rehabilitation, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792 (USA)
    3. Department of Pharmacology, University of Wisconsin, 1300 University Avenue, Madison, WI 53706 (USA)
    4. Collaborative Research Center, AO Foundation
    • Department of Biomedical Engineering, University of Wisconsin, 1550 Engineering Drive, Madison, WI 53706 (USA).
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Abstract

original image

On p. 5494, William L. Murphy and co-workers report on a biomimetic peptide capable of binding hydroxapatite and promoting pro-angiogenic activity including endothelial cell growth and migration. Such a peptide could form a key material for growing, and healing bone tissue.

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