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Graphene-Encapsulated Nanoparticle-Based Biosensor for the Selective Detection of Cancer Biomarkers

Authors

  • Sung Myung,

    1. Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
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  • Aniruddh Solanki,

    1. Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
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  • Cheoljin Kim,

    1. Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
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  • Jaesung Park,

    1. Center for Superfunctional Materials, Department of Chemistry, Pohang University of Science and Technology, Pohang, Korea
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  • Kwang S. Kim,

    1. Center for Superfunctional Materials, Department of Chemistry, Pohang University of Science and Technology, Pohang, Korea
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  • Ki-Bum Lee

    Corresponding author
    1. Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    2. Institute for Advanced Materials, Devices and Nanotechnology (IAMDN), Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    • Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
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Abstract

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Biosensors, based on graphene-encapsulated nanoparticle arrays, for highly sensitive and selective detection of breast cancer biomarkers are successfully demonstrated. The increased surface-to-volume ratio significantly helped in lowering the detection limits (1 pM) for the target biomarkers. In addition, the highly selective nature of the biosensor is demonstrated by detecting low concentrations of the target biomarkers.

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