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Keywords:

  • shape-memory polymers;
  • dynamic cell culture;
  • surface topography;
  • mesenchymal stem cells;
  • polycaprolactone
Thumbnail image of graphical abstract

Poly(ϵ-caprolactone) (PCL) shape-memory polymer (SMP) microarrays are a novel means to investigate the effect of dynamic topography on human mesenchymal stem cell (hMSC) morphology. The synthesis and characterization of oligo-precursors and PCL networks is described. The PCL surfaces demonstrate excellent surface shape-memory properties, minimal cytotoxicity, and excellent control over hMSC morphology.