Advanced Materials

Triggered Cell Release from Materials Using Bioadhesive Photocleavable Linkers

Authors

  • Melanie Wirkner,

    1. Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany
    Search for more papers by this author
  • José María Alonso,

    1. Max Planck Institute für Metallforschung, Heisenbergstrasse 3, 70569 Stuttgart, Germany
    Current affiliation:
    1. CIC nanoGUNE Consolider, Tolosa Hiribidea, 76, 20018 San Sebastián, Spain
    Search for more papers by this author
  • Verona Maus,

    1. Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany
    Search for more papers by this author
  • Marcelo Salierno,

    1. Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany
    Search for more papers by this author
  • Ted T. Lee,

    1. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332–0363, USA
    2. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332–0363, USA
    Search for more papers by this author
  • Andrés J. García,

    1. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332–0363, USA
    2. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332–0363, USA
    Search for more papers by this author
  • Aránzazu del Campo

    Corresponding author
    1. Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany
    • Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany.
    Search for more papers by this author

Abstract

A light-controlled method for cell release by means of surface modification with photolabile linkers is presented. This approach is applicable to any material, provided that the linker is properly designed, and provides direct control over the molecular interactions involved in cell adhesion.

original image

Ancillary