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Protection and Promotion of UV Radiation-Induced Liposome Leakage via DNA-Directed Assembly with Gold Nanoparticles

Authors

  • Neeshma Dave,

    1. Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, N2L 3G1, Canada
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  • Juewen Liu

    Corresponding author
    1. Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, N2L 3G1, Canada
    • Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, N2L 3G1, Canada.
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Abstract

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DNA-functionalized gold nanoparticles and liposomes are assembled by a linker DNA. The gold nanoparticles can either protect the liposome from UV radiation induced leakage or can promote the leakage, depending on the DNA sequence and the alignment of the particles.

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