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Advanced Materials

Organic Electrochemical Transistors Integrated in Flexible Microfluidic Systems and Used for Label-Free DNA Sensing

Authors

  • Peng Lin,

    1. Department of Applied Physics and Materials Research Centre, The Hong Kong Polytechnic University, Hong Kong, China
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  • Xiaoteng Luo,

    1. Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology, Clear Water Bay Kowloon, Hong Kong, China
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  • I-Ming Hsing,

    1. Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology, Clear Water Bay Kowloon, Hong Kong, China
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  • Feng Yan

    Corresponding author
    1. Department of Applied Physics and Materials Research Centre, The Hong Kong Polytechnic University, Hong Kong, China
    • Department of Applied Physics and Materials Research Centre, The Hong Kong Polytechnic University, Hong Kong, China.
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Abstract

Organic electrochemical transistors are integrated in flexible microfluidic systems. A novel label-free DNA sensor is developed based on the devices with single-stranded DNA probes immobilized on gate electrodes. These devices successfully detect complementary DNA targets at low concentrations using a pulse-enhanced hybridization technique in microfluidic channels. Organic electrochemical transistors are excellent candidates for flexible, highly sensitive, and low-cost biosensors.

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