Advanced Materials

Functionalized Conducting Polymer Nanodots for Enhanced Cell Capturing: The Synergistic Effect of Capture Agents and Nanostructures

Authors

  • Jun Sekine,

    1. Yu Initiative Research Unit, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan
    Search for more papers by this author
  • Shyh-Chyang Luo,

    1. Yu Initiative Research Unit, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan
    Search for more papers by this author
  • Shutao Wang,

    1. Beijing National Laboratory of Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, No.2, Zhongguancun North First Street, Beijing, P. R. China
    Search for more papers by this author
  • Bo Zhu,

    1. Yu Initiative Research Unit, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan
    Search for more papers by this author
  • Hsian-Rong Tseng,

    1. Crump Institute for Molecular Imaging (CIMI), Institute for Molecular Medicine (IMED), Department of Molecular and Medical Pharmacology, California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Building 114, Los Angeles, CA 90095-1770, USA
    Search for more papers by this author
  • Hsiao-hua Yu

    Corresponding author
    1. Yu Initiative Research Unit, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan
    • Yu Initiative Research Unit, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
    Search for more papers by this author

Abstract

Nanostructured conducting polymer nanodots are prepared by electropolymerization of carboxylic acid group functionalized monomer in dichloromethane directly onto substrates. They demonstrate enhanced yields for the capture of tumor cells compared to smooth surfaces due to a synergistic effect of the capture agents and nanostructures.

original image

Ancillary