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Advanced Materials

Viscosity Gradient as a Novel Mechanism for the Centrifugation-Based Separation of Nanoparticles

Authors

  • Penghe Qiu,

    1. Department of Chemistry and Biochemistry, University of Oklahoma, Stephenson Life Science Research Center, 101 Stephenson Parkway, Norman, OK, 73019, USA
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  • Chuanbin Mao

    Corresponding author
    1. Department of Chemistry and Biochemistry, University of Oklahoma, Stephenson Life Science Research Center, 101 Stephenson Parkway, Norman, OK, 73019, USA
    • Department of Chemistry and Biochemistry, University of Oklahoma, Stephenson Life Science Research Center, 101 Stephenson Parkway, Norman, OK, 73019, USA.

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Abstract

A novel viscosity gradient, built by stacking aqueous solutions of polyvinylpyrrolidone (PVP), is introduced to achieve precise size separation of nanoparticles. The viscosity gradient is more powerful than the conventional density gradient in separating larger nanoparticles. Nanoparticles that aggregate in PVP solutions are successfully stabilized and separated by size.

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