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Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles

Authors

  • Tae-Jong Yoon,

    1. Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
    2. Department of Applied Bioscience, CHA University, Seoul 135-081, Republic of Korea
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  • Hakho Lee,

    Corresponding author
    1. Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
    • Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA.
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  • Huilin Shao,

    1. Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
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  • Scott A. Hilderbrand,

    1. Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
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  • Ralph Weissleder

    Corresponding author
    1. Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
    2. Department of Systems Biology, Harvard Medical School, 200 Longwood Ave., Alpert 536 Boston, MA 02115, USA
    • Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA.
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Abstract

Highly potent magnetic nanomaterials are developed by encasing multiple magnetic cores inside a thin silica shell, in much the same way as the pomegranate fruit contains many seeds within a thin skin. This construct not only produces materials that are biocompatible but also ones that reach theoretically maximum transverse relaxivity.

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