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Ultrasensitive Diagnosis for an Anthrax-Protective Antigen Based on a Polyvalent Directed Peptide Polymer Coupled to Zinc Oxide Nanorods

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A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDPP) exhibits increased binding affinity and detects anthrax protective antigen at low levels using a well-known zinc oxide nanorod detection system.

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