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Keywords:

  • patchy particles;
  • layer-by-layer;
  • film stiffness;
  • gold nanoparticles
Thumbnail image of graphical abstract

Patchy particles are fabricated using a method of embedding-into and extracting-from thick, biocompatible, gel-like HA/PLL films. Control over the patchiness is achieved by adjusting the stiffness of films, which affects embedding and masking of particles. The stiffness is adjusted by the concentration of gold nanoparticles adsorbed onto the surface of the films.