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Keywords:

  • drug delivery;
  • transient networks;
  • biomedical applications;
  • self-assembly;
  • supramolecular polymers
Thumbnail image of graphical abstract

A modular one-component supramolecular transient network in water, based on poly(ethylene glycol) and end-capped with four-fold hydrogen bonding units, is reported. Due to its nonlinear structural formation, this system allows active proteins to be added to the hydrogel during formation. Once implanted in vivo it releases the protein by erosion of both the protein and polymer via dissolution.