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Controlled Hierarchical Architecture in Surface-initiated Zwitterionic Polymer Brushes with Structurally Regulated Functionalities

Authors

  • Chun-Jen Huang,

    1. Department of Chemical Engineering, University of Washington, Box 351750, Seattle, Washington 98195-1750, USA
    Current affiliation:
    1. Equal contribution to this work.
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    • Graduate Institute of Biomedical Engineering, National Central University, Jhongli, Taiwan

  • Norman D. Brault,

    1. Department of Chemical Engineering, University of Washington, Box 351750, Seattle, Washington 98195-1750, USA
    Current affiliation:
    1. Equal contribution to this work.
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  • Yuting Li,

    1. Department of Chemical Engineering, University of Washington, Box 351750, Seattle, Washington 98195-1750, USA
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  • Qiuming Yu,

    1. Department of Chemical Engineering, University of Washington, Box 351750, Seattle, Washington 98195-1750, USA
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  • Shaoyi Jiang

    Corresponding author
    1. Department of Chemical Engineering, University of Washington, Box 351750, Seattle, Washington 98195-1750, USA
    • Department of Chemical Engineering, University of Washington, Box 351750, Seattle, Washington 98195-1750, USA.
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Abstract

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Hierarchical polymer films with structurally regulated functionalities are achieved by integrating 2D and 3D structures to enable ultralow nonspecific protein binding and high loading of molecular recognition elements, such as antibodies.

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