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Keywords:

  • plasma immersion ion implantation;
  • polytetrafluoroethylene;
  • surface properties;
  • mesenchymal stem cells;
  • osteogenic differentiation
Thumbnail image of graphical abstract

By altering the surface properties of polytetrafluoroethylene (PTFE) substrates using a special PIII technique, mesenchymal stem cells (MSCs) proliferation and osteogenesis can be promoted in culture without osteogenic supplements. The structures are created intrinsically in the PTFE for no risk of materials delamination. Large-scale features and locally different functions can also be readily produced on the same substrate by this technique.