Advanced Materials

Regulating Foreign-Body Responses: Development of Cationic Polymer Coatings to Regulate Foreign-Body Responses (Adv. Mater. 24/2011)

Authors

  • Minglin Ma,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Anesthesiology, Children Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
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  • Wendy F. Liu,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Anesthesiology, Children Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
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  • Paulina S. Hill,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
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  • Kaitlin M. Bratlie,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Anesthesiology, Children Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
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  • Daniel J. Siegwart,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
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  • Justin Chin,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
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  • Miri Park,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Anesthesiology, Children Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
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  • Joao Guerreiro,

    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
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  • Daniel G. Anderson

    Corresponding author
    1. David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    2. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    3. Division of Health Science Technology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA
    4. Department of Anesthesiology, Children Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    • David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
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Abstract

Daniel G. Anderson and coworkers, on p. H189, synthesized a library of cationic polymers that drastically affect the morphology and behavior of monocyte/macrophage cells in vitro when immobilized on a surface, and modulate early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign body responses.

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