Advanced Materials

“Smart” Capsules for Drug Release: Charge-Shifting Click Capsules with Dual-Responsive Cargo Release Mechanisms (Adv. Mater. 36/2011)

Authors

  • Kang Liang,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
    Current affiliation:
    1. K.L. and G.K.S. contributed equally to this work.
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  • Georgina K. Such,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
    Current affiliation:
    1. K.L. and G.K.S. contributed equally to this work.
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  • Zhiyuan Zhu,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
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  • Yan Yan,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
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  • Hannah Lomas,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
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  • Frank Caruso

    Corresponding author
    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
    • Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.
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Abstract

Triggered release systems based on physiological stimuli have emerged for advanced therapeutic delivery applications. On page H273, Frank Caruso and co-workers combine several independent release mechanisms that synergistically function to tune cargo release profi les. The simple and efficient synthesis allows the design of “smart” capsules with dual stimuliresponsive cargo release mechanisms for therapeutic applications.

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