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Keywords:

  • porous silicon;
  • E-selectin;
  • thioaptamers;
  • nanomedicine;
  • bone marrow
Thumbnail image of graphical abstract

The application of a multistage drug-delivery system comprising biodegradable nanoporous silicon particles that allow for a site-specific delivery of different imaging or therapeutic nanoparticles is presented by Mauro Ferrari and co-workers on page H278. The image shows a silicon particle that releases a therapeutic payload into bone marrow tissue.