Nanoemulsion Composite Microgels for Orthogonal Encapsulation and Release

Authors

  • Harry Z. An,

    1. Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 66-270, Cambridge, MA 02139, USA
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Matthew E. Helgeson,

    1. Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 66-270, Cambridge, MA 02139, USA
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Patrick S. Doyle

    Corresponding author
    1. Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 66-270, Cambridge, MA 02139, USA
    • Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 66-270, Cambridge, MA 02139, USA.
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Abstract

original image

Crosslinkable nanoemulsions are combined with flow lithography for the synthesis of structured composite microgels with controlled hydrophobic compartments. The microgels are used to demonstrate a number of motifs for controlled encapsulation and release of active compounds, including small molecules, proteins, and nanoparticles, from a single material platform.

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