Preparation of Porous Collagen Scaffolds with Micropatterned Structures

Authors

  • Hwan Hee Oh,

    1. Tissue Regeneration Materials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
    2. Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan
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  • Young-Gwang Ko,

    1. Tissue Regeneration Materials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
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  • Hongxu Lu,

    1. Tissue Regeneration Materials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
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  • Naoki Kawazoe,

    1. Tissue Regeneration Materials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
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  • Guoping Chen

    Corresponding author
    1. Tissue Regeneration Materials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
    2. Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan
    • Tissue Regeneration Materials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.
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Abstract

original image

Porous collagen scaffolds with micropatterned structures are manufactured using preformed ice micropattern templates. The scaffolds show precisely controlled pore structures and micropattern structures of bioactive substances, which can be tethered by designing a program.

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