Get access

Biologically Responsive Polymeric Nanoparticles for Drug Delivery

Authors

  • Yolonda L. Colson,

    Corresponding author
    1. Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA 02215, USA
    • Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA 02215, USA
    Search for more papers by this author
  • Mark W. Grinstaff

    Corresponding author
    1. Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA 02215, USA
    • Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA 02215, USA.
    Search for more papers by this author

Abstract

Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.

Ancillary