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Advanced Materials

Hybrid 2D Nanomaterials as Dual-Mode Contrast Agents in Cellular Imaging

Authors

  • Tharangattu N. Narayanan,

    1. Department of Mechanical Engineering and Materials Science, Rice University, 6100 Main Street, Houston, TX 77006, USA
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  • Bipin K. Gupta,

    1. National Physical Laboratory (CSIR), Dr. K. S. Krishnan Road, New Delhi 110012, India
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  • Sajna A. Vithayathil,

    1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
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  • Rebeca R. Aburto,

    1. Department of Mechanical Engineering and Materials Science, Rice University, 6100 Main Street, Houston, TX 77006, USA
    2. Department of Molecular Pathology, MD Anderson Cancer Center, 7435 Fannin Street, Unit # 951, Houston, TX 77054, USA
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  • Sendurai A. Mani,

    1. Department of Molecular Pathology, MD Anderson Cancer Center, 7435 Fannin Street, Unit # 951, Houston, TX 77054, USA
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  • Jaime Taha-Tijerina,

    1. Department of Mechanical Engineering and Materials Science, Rice University, 6100 Main Street, Houston, TX 77006, USA
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  • Bin Xie,

    1. Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA
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  • Benny A. Kaipparettu,

    1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    2. Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
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  • Suzy V. Torti,

    1. Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA
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  • Pulickel M. Ajayan

    Corresponding author
    1. Department of Mechanical Engineering and Materials Science, Rice University, 6100 Main Street, Houston, TX 77006, USA
    • Department of Mechanical Engineering and Materials Science, Rice University, 6100 Main Street, Houston, TX 77006, USA.
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Abstract

A biocompatible hybrid 2D nanomaterial based on graphene oxide and superparamagnetic Fe3O4 is demonstrated as a multimodality contrast enhancement agent for cellular imaging using photoluminescence and magnetic resonance imaging. This provides the possibility to use graphene oxide based multimodality and/or multitasking agents for biomedical applications.

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